[P-003]Acute Urinary Retention After Venlafaxine Use: A Rare CaseŞaban Oğuz Demirdöğen1, Esen Yıldırım Demirdöğen2, Şenol Adanur1, Özkan Polat12Department of Child and Adolescent Psychiatric and Diseases, Ataturk University, Erzurum OBJECTIVE: We present a case where lower urinary system symptoms(LUSS) and acute urinary retention developed after increasing dose of venlafaxine. CASE: A 48-year-old male patient with a diagnosis of major depression presented to our clinic with symptoms of difficulty urinating, intermittent stream, and trickling at the end of the urination, together with the inability to urinate that had lasted about 20 hours. The symptoms had started after the venlafaxine he used at a dose of 37.5 mg twice a day was increased to 75 mg twice a day 1.5 months ago. Vesical globe was found on physical examination. Vital signs, laboratory results and radiological images were normal. A transurethral catheter (TU) was placed as the patient had a vesical globe. No urogenital system pathology that could explain the current condition was found and a psychiatry consultation was therefore requested to evaluate the relationship of the problem with the venlafaxine treatment. The psychiatry department thought the present symptoms were associated with venlafaxine and the medication was discontinued gradually. The patient was started agomelatin, which is a melatoninergic receptor agonist antidepressant. The symptoms had disappeared completely 10 days later. Qmax was 19.3 and PVR 10 cc on uroflowmetry. CONCLUSION: We concluded that LUSS and urinary retention had been due to the venlafaxine treatment. It should be used carefully in patients with accompanying prostate disease or micturition disorders. |